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Statistics and reproducibility Where applicable, protein abundance and fluorescence intensities were normalized to the values calculated for the controls as described in each figure legend and analyzed with bilateral Students T -tests (two-tailed distribution and homoscedastic) on Excel (Microsoft Office 365)

Changes in glutathione levels have been implicated in a range of diseases and conditions, including cancer, liver diseases, and neurodegenerative disorders

The major NAD + consumer, the DNA repairing enzyme poly ADP-ribose polymerase (PARP) was then investigated

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